851278-60-9
Chemical Structure
Striatisporolide A
- CAS No.: 851278-60-9
- Formula:C11H16O4
- Molecular Weight:212.24
InChIKey: OIUPBOONLQPLQI-QMMMGPOBSA-N
SMILES: CCCCC[C@H]1C(C(O)=O)=C(C(O1)=O)C
Biological Activity: Striatisporolide A is an antibacterial agent. Striatisporolide A exhibits antibacterial activity against Escherichia coli in vitro. Striatisporolide A damages the cell wall and cell membrane of Escherichia coli, and induces changes in protein levels and morphology. Striatisporolide A reduces the level of apoptosis (apoptosis) in HUVECs, inhibits excessive production of ROS, and possesses pro-proliferative and mild cytoprotective effects. Striatisporolide A can be used in studies related to bacterial infections and degenerative diseases[1][2].
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Striatisporolide A | Striatisporolide A is an antibacterial agent. Striatisporolide A exhibits antibacterial activity against Escherichia coli in vitro. Striatisporolide A damages the cell wall and cell membrane of Escherichia coli, and induces changes in protein levels and morphology. Striatisporolide A reduces the level of apoptosis (apoptosis) in HUVECs, inhibits excessive production of ROS, and possesses pro-proliferative and mild cytoprotective effects. Striatisporolide A can be used in studies related to bacterial infections and degenerative diseases. | |||||||||||||||||||||
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- [1]. Sheng JW, et al. Striatisporolide A, a butenolide metabolite from Athyrium multidentatum (Doll.) Ching, as a potential antibacterial agent. Mol Med Rep. 2019;20(1):198-204. [Content Brief]
- [2]. Liu DM, et al. Cytoproliferative and Cytoprotective Effects of Striatisporolide A Isolated from Rhizomes of Athyrium multidentatum (Doell.) Ching on Human Umbilical Vein Endothelial Cells. Molecules. 2016;21(10):1280. Published 2016 Sep 24. [Content Brief]
Keywords
