85287-61-2
Chemical Structure
Cefpimizole sodium
Synonym(s): U-63196E sodium; AC-1370 sodium
- CAS No.: 85287-61-2
- Formula:C28H25N6NaO10S2
- Molecular Weight:692.65
IUPAC Name: sodium (6R,7R)-7-((R)-2-(5-carboxy-1H-imidazole-4-carboxamido)-2-phenylacetamido)-8-oxo-3-((4-(2-sulfonatoethyl)pyridin-1-ium-1-yl)methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
InChIKey: JLUNZNNMKVKUOH-MRMAQRIOSA-M
SMILES: [O-]C(C1=C(C[N+]2=CC=C(CCS(=O)(O[Na])=O)C=C2)CS[C@@]([C@@H]3NC([C@@H](C4=CC=CC=C4)NC(C5=C(NC=N5)C(O)=O)=O)=O)([H])N1C3=O)=O
Biological Activity: Cefpimizole (U-63196E) sodium is a broad-spectrum cephalosporin antibiotic. Cefpimizole sodium inhibits many Ampicillin (HY-B0522)-resistant bacteria, and is active against gram-negative species. Cefpimizole sodium augments phagocytosis of macrophages and neutrophils[1][2].
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Cefpimizole sodium | Cefpimizole (U-63196E) sodium is a broad-spectrum cephalosporin antibiotic. Cefpimizole sodium inhibits many Ampicillin (HY-B0522)-resistant bacteria, and is active against gram-negative species. Cefpimizole sodium augments phagocytosis of macrophages and neutrophils. | |||||||||||||||||||||
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- [1]. Neu HC, et al. In vitro activity and beta-lactamase stability of U-63196E, a novel cephalosporin. Antimicrob Agents Chemother. 1983 Sep;24(3):375-82. [Content Brief]
- [2]. Ohnishi H, et al. Effects of AC-1370, a new semisynthetic cephalosporin, on phagocyte functions. Antimicrob Agents Chemother. 1983 Jun;23(6):874-80. [Content Brief]
Keywords
