85597-18-8
85597-18-8
Chemical Structure
5,10-Dideazafolic acid
- CAS. Nr.: 85597-18-8
- Formula:C21H21N5O6
- Molecular Weight:439.42
IUPAC Name: (4-(2-(2-amino-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidin-6-yl)ethyl)benzoyl)-L-glutamic acid
InChIKey: BHDZQFSNQPIPGI-HNNXBMFYSA-N
SMILES: O=C(CC[C@H](NC(C1=CC=C(C=C1)CCC2=CN=C(NC(N)=NC3=O)C3=C2)=O)C(O)=O)O
Biological Activity: 5,10-Dideazafolic acid is a 5,10-dideaza-5,6,7,8-tetrahydrofola analogue, which exhibits some inhibitory activity against glycine amide ribonucleotide formyltransferase (GARFT) (Ki=13 μM)[1].
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5,10-Dideazafolic acid | 5,10-Dideazafolic acid is a 5,10-dideaza-5,6,7,8-tetrahydrofola analogue, which exhibits some inhibitory activity against glycine amide ribonucleotide formyltransferase (GARFT) (Ki=13 μM). | |||||||||||||||||||||
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