864082-48-4
864082-48-4
Chemical Structure
GSK466317A
- CAS No.: 864082-48-4
- Formula:C21H16ClF3N4O2
- Molecular Weight:448.83
IUPAC Name: N-(7-chloro-1H-indazol-5-yl)-2-methyl-6-oxo-4-(4-(trifluoromethyl)phenyl)-1,4,5,6-tetrahydropyridine-3-carboxamide
InChIKey: OYNBTBJATZVIGH-UHFFFAOYSA-N
SMILES: O=C(NC1=CC2=C(C(Cl)=C1)NN=C2)C3=C(NC(CC3C4=CC=C(C=C4)C(F)(F)F)=O)C
Biological Activity: GSK466317A is a PKA inhibitor, with an IC50 of 12.59 μM. GSK466317A also inhibits GRK1, GRK2, and GRK5, with IC50s of 1000, 31.62, and 39.81 μM, respectively[1].
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GSK466317A | GSK466317A is a PKA inhibitor, with an IC50 of 12.59 μM. GSK466317A also inhibits GRK1, GRK2, and GRK5, with IC50s of 1000, 31.62, and 39.81 μM, respectively. | |||||||||||||||||||||
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References
Keywords
