GSK466317A
GSK466317A is a PKA inhibitor, with an IC50 of 12.59 μM. GSK466317A also inhibits GRK1, GRK2, and GRK5, with IC50s of 1000, 31.62, and 39.81 μM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 864082-48-4
- Formula: C21H16ClF3N4O2
- Molecular Weight:448.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
|
GRK2 |
PKA 12.59 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
8 nM
Compound: 16
|
Inhibition of human recombinant ROCK1 expressed in Sf9 cells at 10 mM
Inhibition of human recombinant ROCK1 expressed in Sf9 cells at 10 mM
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[PMID: 17201405] |
Chemical Information
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CAS No. 864082-48-4
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Molecular Weight 448.83
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Formula C21H16ClF3N4O2
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SMILES
O=C(NC1=CC2=C(C(Cl)=C1)NN=C2)C3=C(NC(CC3C4=CC=C(C=C4)C(F)(F)F)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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