GSK466317A
GSK466317A is a PKA inhibitor, with an IC50 of 12.59 μM. GSK466317A also inhibits GRK1, GRK2, and GRK5, with IC50s of 1000, 31.62, and 39.81 μM, respectively.
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- CAS. Nr.: 864082-48-4
- Formel: C21H16ClF3N4O2
- Molecular Weight:448.83
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
GRK2 |
PKA 12.59 μM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
8 nM
Compound: 16
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Inhibition of human recombinant ROCK1 expressed in Sf9 cells at 10 mM
Inhibition of human recombinant ROCK1 expressed in Sf9 cells at 10 mM
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[PMID: 17201405] |
Chemical Information
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CAS. Nr. 864082-48-4
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Molecular Weight 448.83
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Formel C21H16ClF3N4O2
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SMILES
O=C(NC1=CC2=C(C(Cl)=C1)NN=C2)C3=C(NC(CC3C4=CC=C(C=C4)C(F)(F)F)=O)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
GSK466317A Related Classifications
HY-119232 Related Classifications
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