86639-62-5
Chemical Structure
10-Nitrocamptothecin
- CAS No.: 86639-62-5
- Formula:C20H15N3O6
- Molecular Weight:393.35
IUPAC Name: (S)-4-ethyl-4-hydroxy-9-nitro-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione
InChIKey: XLHNAFUKOSPOAT-FQEVSTJZSA-N
SMILES: O=C1N2C(C(C(C2)=CC3=C4)=NC3=CC=C4[N+]([O-])=O)=CC5=C1COC([C@]5(O)CC)=O
Biological Activity: 10-Nitrocamptothecin is a topoisomerase I inhibitor with an IC50 of 0.64 μM. 10-Nitrocamptothecin interferes with the formation of cleavable complexes, thereby inhibiting the activity of Topoisomerase I. 10-Nitrocamptothecin is applicable for cancer research[1].
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10-Nitrocamptothecin | 10-Nitrocamptothecin is a topoisomerase I inhibitor with an IC50 of 0.64 μM. 10-Nitrocamptothecin interferes with the formation of cleavable complexes, thereby inhibiting the activity of Topoisomerase I. 10-Nitrocamptothecin is applicable for cancer research. | |||||||||||||||||||||
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Keywords
