866399-89-5
Chemical Structure
Obicetrapib hemicalcium
Synonym(s): TA-8995 hemicalcium; DEZ-001 hemicalcium; AMG-899 hemicalcium
- CAS No.: 866399-89-5
- Formula:C32H31F9N4O5·1/2Ca
- Molecular Weight:742.65
SMILES: FC(F)(F)C1=CC(C(F)(F)F)=CC(CN(C2=NC=C(OCCCC(O)=O)C=N2)[C@@H]3C4=CC(C(F)(F)F)=CC=C4N([C@@H](C3)CC)C(OCC)=O)=C1.[Ca].[1/2]
Biological Activity: Obicetrapib hemicalcium (TA-8995; DEZ-001) is an orally active cholesteryl ester transfer protein (CETP) inhibitor. Obicetrapib hemicalcium potently reduces atherogenic lipoproteins (such as LDL-C, ApoB, Lp (a)) and increases HDL-C. Obicetrapib hemicalcium can be used for the research of dyslipidemia and atherosclerotic cardiovascular disease (ASCVD)[1].
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Obicetrapib hemicalcium | Obicetrapib hemicalcium (TA-8995; DEZ-001) is an orally active cholesteryl ester transfer protein (CETP) inhibitor. Obicetrapib hemicalcium potently reduces atherogenic lipoproteins (such as LDL-C, ApoB, Lp (a)) and increases HDL-C. Obicetrapib hemicalcium can be used for the research of dyslipidemia and atherosclerotic cardiovascular disease (ASCVD). | |||||||||||||||||||||
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