86703-02-8
Chemical Structure
Mopidralazine hydrochloride
Synonym(s): MDL-899
- CAS No.: 86703-02-8
- Formula:C14H20ClN5O
- Molecular Weight:309.79
IUPAC Name: N-(2,5-dimethyl-1H-pyrrol-1-yl)-6-morpholinopyridazin-3-amine hydrochloride
InChIKey: IHQNCEYNGSNDAD-UHFFFAOYSA-N
SMILES: CC1=CC=C(C)N1NC2=NN=C(N3CCOCC3)C=C2.Cl
Biological Activity: Mopidralazine hydrochloride (MDL-899) (Compound 30) is an orally active antihypertensive agent. Mopidralazine hydrochloride significantly reduces systolic blood pressure (ED50 = 1.94 mg/kg) in spontaneously hypertensive rats models. Mopidralazine hydrochloride has a slower onset of action but a longer duration of action and has a significantly smaller effect on increasing heart rate in canine model of renal hypertension. Mopidralazine hydrochloride can be used for the research of hypertension[1].
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Mopidralazine hydrochloride | Mopidralazine hydrochloride (MDL-899) (Compound 30) is an orally active antihypertensive agent. Mopidralazine hydrochloride significantly reduces systolic blood pressure (ED50 = 1.94 mg/kg) in spontaneously hypertensive rats models. Mopidralazine hydrochloride has a slower onset of action but a longer duration of action and has a significantly smaller effect on increasing heart rate in canine model of renal hypertension. Mopidralazine hydrochloride can be used for the research of hypertension. | |||||||||||||||||||||
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