87075-23-8
87075-23-8
Chemical Structure
Aerophobin-2
- CAS No.: 87075-23-8
- Formula:C16H19Br2N5O4
- Molecular Weight:505.16
IUPAC Name: (5S,10R)-N-(3-(2-amino-1H-imidazol-5-yl)propyl)-7,9-dibromo-10-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]deca-2,6,8-triene-3-carboxamide
InChIKey: ZSZRBAQVYFYMTR-XJKSGUPXSA-N
SMILES: O[C@@H]1[C@@]2(C=C(C(OC)=C1Br)Br)CC(C(NCCCC3=CN=C(N3)N)=O)=NO2
Biological Activity: Aerophobin-2 is a bromine compound, which can be isolated from sponge Verongia aerophoba. Aerophobin-2 inhibits aggregation of α-synuclein (α-syn) and phosphorylated α-synuclein (pSyn), exhibits neuroprotective efficacy[1].
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Aerophobin-2 | Aerophobin-2 is a bromine compound, which can be isolated from sponge Verongia aerophoba. Aerophobin-2 inhibits aggregation of α-synuclein (α-syn) and phosphorylated α-synuclein (pSyn), exhibits neuroprotective efficacy. | |||||||||||||||||||||
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References
Keywords
