871313-59-6
871313-59-6
Chemical Structure
JNJ-27141491
- CAS No.: 871313-59-6
- Formula:C17H15F2N3O3S
- Molecular Weight:379.38
IUPAC Name: methyl (S)-3-(1-(3,4-difluorophenyl)propyl)-5-(isoxazol-5-yl)-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxylate
InChIKey: SYARXICKXVXWNA-LBPRGKRZSA-N
SMILES: CC[C@@H](C1=CC(F)=C(F)C=C1)N2C(C(OC)=O)=C(C3=CC=NO3)NC2=S
Biological Activity: JNJ-27141491 is a selective, noncompetitive and orally active functional antagonist of human CCR2[1].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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JNJ-27141491 | 97.01% | JNJ-27141491 is a selective, noncompetitive and orally active functional antagonist of human CCR2. | ||||||||||||||||||||
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References
- [1]. Buntinx M, et al. Pharmacological profile of JNJ-27141491 [(S)-3-[3,4-difluorophenyl)-propyl]-5-isoxazol-5-yl-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxyl acid methyl ester], as a noncompetitive and orally active antagonist of the human chemokine receptor CCR2. J Pharmacol Exp Ther. 2008 Oct;327(1):1-9. [Content Brief]
