871826-47-0
871826-47-0
Chemical Structure
10(S),17(S)-DiHDHA
Synonym(s): 10(S),17(S)-DiHDoHE; PDX
- CAS No.: 871826-47-0
- Formula:C22H32O4
- Molecular Weight:360.49
IUPAC Name: (4Z,7Z,10S,11E,13Z,15E,17S,19Z)-10,17-dihydroxydocosa-4,7,11,13,15,19-hexaenoic acid
InChIKey: CRDZYJSQHCXHEG-XLBFCUQGSA-N
SMILES: CC/C=C\C[C@H](O)/C=C/C=C\C=C\[C@@H](O)C/C=C\C/C=C\CCC(O)=O
Biological Activity: 10(S),17(S)-DiHDHA (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities[1][2].
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10(S),17(S)-DiHDHA | 10(S),17(S)-DiHDHA (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities. | |||||||||||||||||||||
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References
- [1]. Serhan CN, Gotlinger K, Hong S, Lu Y, Siegelman J, Baer T, Yang R, Colgan SP, Petasis NA. Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes. J Immunol. 2006 Feb 1;176(3):1848-59. [Content Brief]
- [2]. Schwab JM, Chiang N, Arita M, Serhan CN. Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature. 2007 Jun 14;447(7146):869-74. [Content Brief]
Keywords
