882853-94-3
Chemical Structure
DCP-Bio1
- CAS. Nr.: 882853-94-3
- Formula:C19H28N2O5S
- Molecular Weight:396.50
InChIKey: ATXZRRQXSLLAAF-HUDLUFLHSA-N
SMILES: O=C(CC(CC1)=O)C1CCCOC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O
Biological Activity: DCP-Bio1 is a targeting labeling reagent for cysteine sulfenic acid (cysteine sulfenic acid). DCP-Bio1 labels protein cysteine sulfenic acid in intact cells via in situ labeling, and also labels cellular proteins during cell lysis. DCP-Bio1 detects sulfenic acid modifications of FLT3 and FLT3ITD in cancer cells. DCP-Bio1 is applicable to research related to sulfenic acid labeling[1][2]
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
DCP-Bio1 | DCP-Bio1 is a targeting labeling reagent for cysteine sulfenic acid (cysteine sulfenic acid). DCP-Bio1 labels protein cysteine sulfenic acid in intact cells via in situ labeling, and also labels cellular proteins during cell lysis. DCP-Bio1 detects sulfenic acid modifications of FLT3 and FLT3ITD in cancer cells. DCP-Bio1 is applicable to research related to sulfenic acid labeling | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Klomsiri C, et al.. Use of dimedone-based chemical probes for sulfenic acid detection evaluation of conditions affecting probe incorporation into redox-sensitive proteins. Methods in enzymology. 2010;473:77-94. [Content Brief]
- [2]. Böhmer A, et al.. Modulation of FLT3 signal transduction through cytoplasmic cysteine residues indicates the potential for redox regulation. Redox biology. 2020 Jan;28:101325. [Content Brief]
Keywords
