883046-50-2
883046-50-2
Chemical Structure
Pichromene
Synonym(s): S14161
- CAS No.: 883046-50-2
- Formula:C17H14FNO4
- Molecular Weight:315.30
IUPAC Name: 8-ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene
InChIKey: BFZXDHIUPNWOMT-UHFFFAOYSA-N
SMILES: O=[N+](C1=CC2=CC=CC(OCC)=C2OC1C3=CC=C(F)C=C3)[O-]
Biological Activity: Pichromene (S14161) is an anticancer agent and weak PI3K inhibitor. Pichromene can effectively inhibit tumor growth in leukemia mouse models and can be used in cancer research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pichromene | 98.0% | Pichromene (S14161) is an anticancer agent and weak PI3K inhibitor. Pichromene can effectively inhibit tumor growth in leukemia mouse models and can be used in cancer research. | ||||||||||||||||||||
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References
- [1]. Mao X, et al. A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway. Blood. 2011 Feb 10;117(6):1986-97. [Content Brief]
- [2]. Fouqué A, et al. A Novel Covalent mTOR Inhibitor, DHM25, Shows in Vivo Antitumor Activity against Triple-Negative Breast Cancer Cells. J Med Chem. 2015 Aug 27;58(16):6559-73. [Content Brief]
Keywords
