883446-27-3
Chemical Structure
LY-2434074
- CAS. Nr.: 883446-27-3
- Formula:C21H33ClF2N2O4
- Molecular Weight:450.95
IUPAC Name: N-((1S,2S)-3-(3,5-difluorophenyl)-1-hydroxy-1-((3R,5S,6R)-5-methyl-6-(neopentyloxy)morpholin-3-yl)propan-2-yl)acetamide hydrochloride
InChIKey: PJQGOUVTIKZTOU-QUQQOIKDSA-N
SMILES: O[C@H]([C@]1([H])N[C@H]([C@@H](OC1)OCC(C)(C)C)C)[C@@H](NC(C)=O)CC2=CC(F)=CC(F)=C2.Cl
Biological Activity: LY-2434074 is a selective β-secretase (BACE) inhibitor with an IC50 <100 nM. LY-2434074 can inhibit amyloid-β (Aβ40 and Aβ42) production. LY-2434074 can be used for the research of neurological disease, such as Alzheimer's disease[1].
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LY-2434074 | LY-2434074 is a selective β-secretase (BACE) inhibitor with an IC50 <100 nM. LY-2434074 can inhibit amyloid-β (Aβ40 and Aβ42) production. LY-2434074 can be used for the research of neurological disease, such as Alzheimer's disease. | |||||||||||||||||||||
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Keywords
