885482-95-1
Chemical Structure
SKS-927
- CAS No.: 885482-95-1
- Formula:C27H27Cl2N5O2
- Molecular Weight:524.44
IUPAC Name: 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(4-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quinoline-3-carbonitrile
InChIKey: ZJDFSJYCAFMEGH-UHFFFAOYSA-N
SMILES: N#CC1=CN=C2C=C(C(OC)=CC2=C1NC3=CC(OC)=C(C=C3Cl)Cl)C#CCCN4CCN(CC4)C
Biological Activity: SKS-927 is a Src kinase inhibitor, with an IC50 value of 3.9 nM. SKS-927 inhibits the proliferation of Src-transformed rat fibroblasta, with an IC50 value of 73 nM. SKS-927 exhibits an IC50 value of 720 nM against EGFR. SKS-927 can be used for the study of cancer and osteoporosis[1].
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SKS-927 | SKS-927 is a Src kinase inhibitor, with an IC50 value of 3.9 nM. SKS-927 inhibits the proliferation of Src-transformed rat fibroblasta, with an IC50 value of 73 nM. SKS-927 exhibits an IC50 value of 720 nM against EGFR. SKS-927 can be used for the study of cancer and osteoporosis. | |||||||||||||||||||||
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Keywords
