89575-11-1
Chemical Structure
AURKA-IN-4
- CAS No.: 89575-11-1
- Formula:C12H17NO3
- Molecular Weight:223.27
InChIKey: HYGXNCVIGJQTAQ-UHFFFAOYSA-N
SMILES: COC1=CC(CNC(CCC)=O)=CC=C1O
Biological Activity: AURKA-IN-4 (compound 13), a capsaicin-derived prohibitin ligand, is an AURKA inhibitor. AURKA-IN-4 acts as a molecular glue within the AURKA/PHB2/LC3 complex. AURKA-IN-4 is specific to the mitochondrial pool of AURKA, and inhibits AURKA-dependent mitophagy. AURKA-IN-4 can be used for cancer research[1].
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AURKA-IN-4 | 99.88% | AURKA-IN-4 (compound 13), a capsaicin-derived prohibitin ligand, is an AURKA inhibitor. AURKA-IN-4 acts as a molecular glue within the AURKA/PHB2/LC3 complex. AURKA-IN-4 is specific to the mitochondrial pool of AURKA, and inhibits AURKA-dependent mitophagy. AURKA-IN-4 can be used for cancer research. | ||||||||||||||||||||
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Keywords