896584-55-7
896584-55-7
Chemical Structure
TRPV1 antagonist 10
- CAS No.: 896584-55-7
- Formula:C16H14N2O5
- Molecular Weight:314.29
InChIKey: XEOBUSLELWJDNO-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(OCCO2)=C2C=C1)NC3=CC=C(OCO4)C4=C3
Biological Activity: TRPV1 antagonist 10 is an orally active and potent TRPV1 antagonist (IC50 = 33.06 nM), moderate to weak URAT1 (IC50 = 22.51 μM) and GLUT9 (60.25% at 50 μM) inhibitor. TRPV1 antagonist 10 has analgesic and urate-lowering effect. TRPV1 antagonist 10 can be studied for research in hyperuricemia and inflammatory pain[1].
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TRPV1 antagonist 10 | 98.54% | TRPV1 antagonist 10 is an orally active and potent TRPV1 antagonist (IC50 = 33.06 nM), moderate to weak URAT1 (IC50 = 22.51 μM) and GLUT9 (60.25% at 50 μM) inhibitor. TRPV1 antagonist 10 has analgesic and urate-lowering effect. TRPV1 antagonist 10 can be studied for research in hyperuricemia and inflammatory pain. | ||||||||||||||||||||
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