918523-75-8

CDK8-IN-13 Chemical Structure
918523-75-8

Chemical Structure

CDK8-IN-13

  • CAS No.: 918523-75-8
  • Formula:C14H11N3O
  • Molecular Weight:237.26

IUPAC Name: 3-(1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide

InChIKey: PQAJMNITAQGSCS-UHFFFAOYSA-N

SMILES: O=C(C1=CC=CC(C2=CN=C3NC=CC3=C2)=C1)N

Biological Activity: CDK8-IN-13 is a potent, selective and orally active CDK8 inhibitor with an IC50 value of 51.9 nM. CDK8-IN-13 induces apoptosis. CDK8-IN-13 decreases the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 shows antitumor activity[1].

Cat. No. Product Name Purity Description Pricing
HY-149974 		CDK8-IN-13 99.14% CDK8-IN-13 is a potent, selective and orally active CDK8 inhibitor with an IC50 value of 51.9 nM. CDK8-IN-13 induces apoptosis. CDK8-IN-13 decreases the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 shows antitumor activity.
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