918523-75-8

CDK8-IN-13 Chemical Structure
918523-75-8

Chemical Structure

CDK8-IN-13

  • CAS No.: 918523-75-8
  • Formula:C14H11N3O
  • Molecular Weight:237.26

IUPAC Name: 3-(1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide

InChIKey: PQAJMNITAQGSCS-UHFFFAOYSA-N

SMILES: O=C(C1=CC=CC(C2=CN=C3NC=CC3=C2)=C1)N

Biological Activity: CDK8-IN-13 is a potent, selective and orally active CDK8 inhibitor with an IC50 value of 51.9 nM. CDK8-IN-13 induces apoptosis. CDK8-IN-13 decreases the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 shows antitumor activity[1].

Cat. No. Product Name Purity Description Pricing
HY-149974 		CDK8-IN-13 99.14% CDK8-IN-13 is a potent, selective and orally active CDK8 inhibitor with an IC50 value of 51.9 nM. CDK8-IN-13 induces apoptosis. CDK8-IN-13 decreases the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 shows antitumor activity.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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