AZ513
AZ513 is a reversible FAAH inhibitor with an IC50s of 551 nM and 27 nM for human FAAH and rat FAAH, respectively. AZ513 inhibits Anandamide (HY-10863) hydrolysis in human FAAH-transfected HEK293 cells (IC50 of 360 nM).
For research use only. We do not sell to patients.
- CAS No.: 1335231-15-6
- Formula: C14H9Cl2N3O
- Molecular Weight:306.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
IC50: 551 nM (human FAAH) and 27 nM (rat FAAH)[1]
Chemical Information
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CAS No. 1335231-15-6
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Molecular Weight 306.15
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Formula C14H9Cl2N3O
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SMILES
O=C(C1=C(Cl)C(Cl)=CC=C1)NC2=CC3=C(NC=C3)N=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)