AZ513
AZ513 is a reversible FAAH inhibitor with an IC50s of 551 nM and 27 nM for human FAAH and rat FAAH, respectively. AZ513 inhibits Anandamide (HY-10863) hydrolysis in human FAAH-transfected HEK293 cells (IC50 of 360 nM).
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- CAS. Nr.: 1335231-15-6
- Formel: C14H9Cl2N3O
- Molecular Weight:306.15
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
IC50: 551 nM (human FAAH) and 27 nM (rat FAAH)[1]
Chemical Information
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CAS. Nr. 1335231-15-6
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Molecular Weight 306.15
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Formel C14H9Cl2N3O
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SMILES
O=C(C1=C(Cl)C(Cl)=CC=C1)NC2=CC3=C(NC=C3)N=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)