92206-54-7
92206-54-7
Chemical Structure
(Rac)-Rotigotine
Synonym(s): N-0437
- CAS No.: 92206-54-7
- Formula:C19H25NOS
- Molecular Weight:315.47
IUPAC Name: 6-(propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
InChIKey: KFQYTPMOWPVWEJ-UHFFFAOYSA-N
SMILES: OC1=C2CCC(CC2=CC=C1)N(CCC3=CC=CS3)CCC
Biological Activity: (Rac)-Rotigotine (N-0437) is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Kis of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.
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(Rac)-Rotigotine | 99.88% | (Rac)-Rotigotine (N-0437) is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Kis of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor. | ||||||||||||||||||||
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