92950-39-5
Chemical Structure
7-Acetyl paclitaxel
- CAS No.: 92950-39-5
- Formula:C49H53NO15
- Molecular Weight:895.94
IUPAC Name: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-4,6,12b(2aH)-triyl triacetate
InChIKey: QHVFIEKTXYELRR-XOVTVWCYSA-N
SMILES: CC(O[C@]([C@@]1([H])C[C@@H]2OC(C)=O)(CO1)[C@]([C@@H]([C@@](C3(C)C)(C[C@@H]4OC([C@H](O)[C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)O)OC(C7=CC=CC=C7)=O)([H])[C@@]2(C([C@@H](C3=C4C)OC(C)=O)=O)C)=O
Biological Activity: 7-Acetyl paclitaxel is a microtubule depolymerization inhibitor which inhibits calcium-induced microtubule depolymerization. 7-Acetyl paclitaxel reduces the growth of J774.2 macrophages (IC50 ~ 60 nM) and increases the levels of nitric oxide (NO) and TNF in isolated mouse peritoneal macrophages[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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7-Acetyl paclitaxel | 98.35% | 7-Acetyl paclitaxel is a microtubule depolymerization inhibitor which inhibits calcium-induced microtubule depolymerization. 7-Acetyl paclitaxel reduces the growth of J774.2 macrophages (IC50 ~ 60 nM) and increases the levels of nitric oxide (NO) and TNF in isolated mouse peritoneal macrophages. | ||||||||||||||||||||
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