946594-19-0
Chemical Structure
BMS-457
- CAS No.: 946594-19-0
- Formula:C24H35ClN2O4
- Molecular Weight:451.00
IUPAC Name: (1R,3R)-N-((R)-1-((S)-4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)-3-methyl-1-oxobutan-2-yl)-3-hydroxycyclopentane-1-carboxamide
InChIKey: WIHIXSCKSFSENF-YBNJHJSASA-N
SMILES: O[C@@]1(C2=CC=C(C=C2)Cl)C(C)(CN(CC1)C([C@@H](C(C)C)NC([C@@H]3CC[C@H](C3)O)=O)=O)C
Biological Activity: BMS-457 is a potent and selective CCR1 antagonist. BMS-457 can be used in the study of rheumatoid arthritis[1].
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BMS-457 | BMS-457 is a potent and selective CCR1 antagonist. BMS-457 can be used in the study of rheumatoid arthritis. | |||||||||||||||||||||
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Keywords