951248-25-2
951248-25-2
Chemical Structure
CJ-036878
- CAS No.: 951248-25-2
- Formula:C22H21NO3
- Molecular Weight:347.41
InChIKey: VZKHCMVEWLIXIC-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C=C1)O)NCC2=CC(OCCC3=CC=CC=C3)=CC=C2
Biological Activity: CJ-036878 is a NMDAR NR2B subunit antagonist. CJ-036878 is applicable to research related to persistent inflammatory pain and neuropathic pain[1][2].
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CJ-036878 | CJ-036878 is a NMDAR NR2B subunit antagonist. CJ-036878 is applicable to research related to persistent inflammatory pain and neuropathic pain. | |||||||||||||||||||||
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References
- [1]. Emoto C, et al. CYP3A4 and CYP3A5 catalyse the conversion of the N-methyl-D-aspartate (NMDA) antagonist CJ-036878 to two novel dimers. Xenobiotica. 2007;37(12):1408-1420. [Content Brief]
- [2]. Nishida H, et al. Metabolism of CJ-036878, N-(3-phenethoxybenzyl)-4-hydroxybenzamide, in liver microsomes and recombinant cytochrome P450 enzymes: metabolite identification by LC-UV/MS(n) and (1)H-NMR. Xenobiotica. 2007 Dec;37(12):1394-407. [Content Brief]
Keywords
