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Cat. No.: HY-182628

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CJ-036878

CJ-036878 is a NMDAR NR2B subunit antagonist. CJ-036878 is applicable to research related to persistent inflammatory pain and neuropathic pain.

For research use only. We do not sell to patients.

CAS No.: 951248-25-2
Formula: C₂₂H₂₁NO₃
Molecular Weight:347.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CJ-036878 Chemical Structure

CAS No.: 951248-25-2

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
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Biological Activity

Description

CJ-036878 is a NMDAR NR2B subunit antagonist. CJ-036878 is applicable to research related to persistent inflammatory pain and neuropathic pain^[1]^[2].

IC₅₀ & Target^[1]

NR2B

All iGluR Isoforms :

In Vitro

CJ-036878 is a NMDAR NR2B subunit antagonist, is applicable to research related to persistent inflammatory pain and neuropathic pain^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 951248-25-2
Molecular Weight 347.41
Formula C₂₂H₂₁NO₃
SMILES

O=C(C1=CC=C(C=C1)O)NCC2=CC(OCCC3=CC=CC=C3)=CC=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Emoto C, et al. CYP3A4 and CYP3A5 catalyse the conversion of the N-methyl-D-aspartate (NMDA) antagonist CJ-036878 to two novel dimers. Xenobiotica. 2007;37(12):1408-1420. [Content Brief]

[2]. Nishida H, et al. Metabolism of CJ-036878, N-(3-phenethoxybenzyl)-4-hydroxybenzamide, in liver microsomes and recombinant cytochrome P450 enzymes: metabolite identification by LC-UV/MS(n) and (1)H-NMR. Xenobiotica. 2007 Dec;37(12):1394-407. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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CJ-036878

All iGluR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CJ-036878 Related Classifications

HY-182628 Related Classifications