952306-31-9
Chemical Structure
Apoptosis inducer 56
- CAS No.: 952306-31-9
- Formula:C11H17N3O3S
- Molecular Weight:271.34
InChIKey: CWJPXABIHMAIES-UHFFFAOYSA-N
SMILES: O=C(CCCCCCC(NO)=O)NC1=NC=CS1
Biological Activity: Apoptosis inducer 56 is an apoptosis inducer. Apoptosis inducer 56 induces DNA damage (upregulation of γH2AX and p-ATM expression) by minor groove binding. Apoptosis inducer 56 induces intrinsic apoptosis (upregulation of p53 and Bax/Bcl-2 ratio, cleaved caspase-7) via S-phase cell cycle arrest. Apoptosis inducer 56 shows selectivity for cancer cells over normal breast epithelial cells. Apoptosis inducer 56 can be used for the research of breast cancer[1].
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Apoptosis inducer 56 | Apoptosis inducer 56 is an apoptosis inducer. Apoptosis inducer 56 induces DNA damage (upregulation of γH2AX and p-ATM expression) by minor groove binding. Apoptosis inducer 56 induces intrinsic apoptosis (upregulation of p53 and Bax/Bcl-2 ratio, cleaved caspase-7) via S-phase cell cycle arrest. Apoptosis inducer 56 shows selectivity for cancer cells over normal breast epithelial cells. Apoptosis inducer 56 can be used for the research of breast cancer. | |||||||||||||||||||||
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Keywords
