954138-07-9
954138-07-9
Chemical Structure
PF-03049423 free base
- CAS No.: 954138-07-9
- Formula:C24H32N6O4
- Molecular Weight:468.55
IUPAC Name: 3-(4-(2-hydroxyethyl)piperazin-1-yl)-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one
InChIKey: MNLNAGRCHNMKKJ-UHFFFAOYSA-N
SMILES: O=C1C(N2CCN(CC2)CCO)=NC3=C(N1CCOCCC)C=C(C4=CC=C(OC)N=C4)N=C3
Biological Activity: PF-03049423 (Compound PF-5) free base is a potent and highly selective phosphodiesterase-5A inhibitor with an IC50 of about 0.2 nM for rat and human platelet enzyme. PF-03049423 free base can be used for the research of acute ischaemic stroke[1].
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PF-03049423 free base | PF-03049423 (Compound PF-5) free base is a potent and highly selective phosphodiesterase-5A inhibitor with an IC50 of about 0.2 nM for rat and human platelet enzyme. PF-03049423 free base can be used for the research of acute ischaemic stroke. | |||||||||||||||||||||
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References
Keywords
