96566-25-5
96566-25-5
Chemical Structure
Ablukast
Synonym(s): Ro 23-3544
- CAS No.: 96566-25-5
- Formula:C28H34O8
- Molecular Weight:498.56
IUPAC Name: 6-acetyl-7-((5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl)oxy)chromane-2-carboxylic acid
InChIKey: FGGYJWZYDAROFF-UHFFFAOYSA-N
SMILES: O=C(O)C1CCC2=CC(C(C)=O)=C(C=C2O1)OCCCCCOC3=CC=C(C(O)=C3CCC)C(C)=O
Biological Activity: Ablukast (Ro 23-3544) is a specific and active leukotriene receptor antagonist. Ablukast effectively reduces LTC4- and antigen-induced bronchoconstriction[1][2]. Ablukast is LTD4 receptor antagonist[3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ablukast | 99.36% | Ablukast (Ro 23-3544) is a specific and active leukotriene receptor antagonist. Ablukast effectively reduces LTC4- and antigen-induced bronchoconstriction. Ablukast is LTD4 receptor antagonist. | ||||||||||||||||||||
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References
- [1]. M O'Donnell, et al. Pharmacological profile of Ro 23-3544, a new aerosol active leukotriene receptor antagonist. Adv Prostaglandin Thromboxane Leukot Res. 1987;17A:512-8. [Content Brief]
- [2]. T Rosenbach, et al. Studies on the role of leukotrienes in murine allergic and irritant contact dermatitis. Br J Dermatol. 1988 Jan;118(1):1-6. [Content Brief]
- [3]. Hans-Michael Eggenweiler, et al. Pyrrolopyrimidines as phosphodiesterase VII inhibitors. US7498334B2.
Keywords
