97901-22-9
97901-22-9
Chemical Structure
Nafagrel hydrochloride
- CAS No.: 97901-22-9
- Formula:C15H17ClN2O2
- Molecular Weight:292.76
IUPAC Name: 6-((1H-imidazol-1-yl)methyl)-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid hydrochloride
InChIKey: DRWRJLPMUWWEHY-UHFFFAOYSA-N
SMILES: OC(C1=CC=C(CC(CN2C=CN=C2)CC3)C3=C1)=O.Cl
Biological Activity: Nafagrel hydrochloride is a thromboxane A2 synthetase inhibitor. Nafagrel hydrochloride can prevent the accumulation of thrombus material in a rat model of acute arterial thrombosis[1][2].
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Nafagrel hydrochloride | Nafagrel hydrochloride is a thromboxane A2 synthetase inhibitor. Nafagrel hydrochloride can prevent the accumulation of thrombus material in a rat model of acute arterial thrombosis. | |||||||||||||||||||||
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References
- [1]. Geiger J. Inhibitors of platelet signal transduction as anti-aggregatory drugs. Expert Opin Investig Drugs. 2001 May;10(5):865-90. [Content Brief]
- [2]. Bernat A, et al. Effect of various antiplatelet agents on acute arterial thrombosis in the rat. Thromb Haemost. 1993 Nov 15;70(5):812-6. [Content Brief]
Keywords
