cFMS Receptor Inhibitor IV
Based on 1 Customer Validation
cFMS Receptor Inhibitor IV (Compound 42) is a potent cFMS inhibitor with an IC50 of 0.017 μM.
For research use only. We do not sell to patients.
- Purity: 99.61%
- CAS No.: 959626-45-0
- Formula: C22H26N4O2
- Molecular Weight:378.47
-
Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Bioactive Compound Library Max
HY-L181
-
Bioactive Compound Library
HY-L001
-
Immunology/Inflammation Compound Library
HY-L007
-
Kinase Inhibitor Library
HY-L009
-
Protein Tyrosine Kinase Compound Library
HY-L016
-
Membrane Protein-targeted Compound Library
HY-L149
-
Cytokine Inhibitors Library
HY-L161
-
Macrophage Related Compound Library
HY-L174
-
MCE Bioactive Compound Library
HY-L001V
-
Anti-Brain Cancer Compound Library
HY-L188
-
Protein Kinase Compound Library
HY-L196
-
Cell Proliferation Compound Library
HY-L201
-
High-Throughput Bioactive Compound Library
HY-L205
-
Posttranslational Modification Library
HY-L226
Biological Activity
IC50: 0.017 μM (cFMS)[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
0.076 μM
Compound: 42
|
Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cells
Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase in HEK 293 cells
|
[PMID: 17904845] |
Chemical Information
-
CAS No. 959626-45-0
-
Appearance Solid
-
Molecular Weight 378.47
-
Formula C22H26N4O2
-
Color Light yellow to yellow
-
SMILES
O=C(C1=CC=C(C#N)O1)NC2=CC(N3CCCCC3)=CC=C2N4CCCCC4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 31.25 mg/mL (82.57 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6422 mL | 13.2111 mL | 26.4222 mL | 66.0554 mL |
| 5 mM | 0.5284 mL | 2.6422 mL | 5.2844 mL | 13.2111 mL | |
| 10 mM | 0.2642 mL | 1.3211 mL | 2.6422 mL | 6.6055 mL | |
| 15 mM | 0.1761 mL | 0.8807 mL | 1.7615 mL | 4.4037 mL | |
| 20 mM | 0.1321 mL | 0.6606 mL | 1.3211 mL | 3.3028 mL | |
| 25 mM | 0.1057 mL | 0.5284 mL | 1.0569 mL | 2.6422 mL | |
| 30 mM | 0.0881 mL | 0.4404 mL | 0.8807 mL | 2.2018 mL | |
| 40 mM | 0.0661 mL | 0.3303 mL | 0.6606 mL | 1.6514 mL | |
| 50 mM | 0.0528 mL | 0.2642 mL | 0.5284 mL | 1.3211 mL | |
| 60 mM | 0.0440 mL | 0.2202 mL | 0.4404 mL | 1.1009 mL | |
| 80 mM | 0.0330 mL | 0.1651 mL | 0.3303 mL | 0.8257 mL |
cFMS Receptor Inhibitor IV Related Classifications
HY-112455 Related Classifications
Powered by Bioz