17-Hydroxyjolkinolide A
17-Hydroxyjolkinolide A (Caudicifolin; Fischeriana A) is an insect feeding inhibitor isolated from the roots of spurge. 17-Hydroxyjolkinolide A induces grain aversion in S. zeamais and T. castaneum adults, with EC50s of 631.9 ppm and 656.5 ppm, respectively.
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- CAS. Nr.: 65388-16-1
- Formel: C20H26O4
- Molecular Weight:330.42
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
9.1 μM
Compound: 14
|
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by Griess assay
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by Griess assay
|
[PMID: 31180680] |
| HCT-15 | IC50 |
13 μM
Compound: 6e
|
Cytotoxicity against human HCT-15 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human HCT-15 cells incubated for 48 hrs by MTT assay
|
[PMID: 33289552] |
| LNCaP C4-2B | IC50 |
2.2 μM
Compound: 6e
|
Cytotoxicity against human LNCaP C4-2B cells incubated for 48 hrs by MTT assay
Cytotoxicity against human LNCaP C4-2B cells incubated for 48 hrs by MTT assay
|
[PMID: 33289552] |
| MDA-MB-231 | IC50 |
8.8 μM
Compound: 6e
|
Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
|
[PMID: 33289552] |
Chemical Information
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CAS. Nr. 65388-16-1
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Molecular Weight 330.42
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Formel C20H26O4
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SMILES
C[C@]12[C@@]3([H])[C@@]4(CC[C@]1([H])C(C)(CCC2)C)[C@](C(C(O5)=C3)=C(CO)C5=O)([H])O4
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Synonyms
Caudicifolin; Fischeriana A
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)