3-Hydroxy carvedilol
3-Hydroxy carvedilol is an active compound.
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- CAS. Nr.: 146574-43-8
- Formel: C24H26N2O5
- Molecular Weight:422.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
9.4 μM
Compound: 2; BM-910228; SB 211475
|
Inhibition of RyR2 R4496C mutant-mediated store overload-induced calcium release in HEK293 cells assessed as reduction in amplitude of spontaneous calcium oscillations by fura-2 AM dye based fluorescence assay
Inhibition of RyR2 R4496C mutant-mediated store overload-induced calcium release in HEK293 cells assessed as reduction in amplitude of spontaneous calcium oscillations by fura-2 AM dye based fluorescence assay
|
[PMID: 26584883] |
Chemical Information
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CAS. Nr. 146574-43-8
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Molecular Weight 422.47
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Formel C24H26N2O5
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SMILES
OC1=C(OCC(CNCCOC2=C(OC)C=CC=C2)O)C3=C(NC4=C3C=CC=C4)C=C1
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Synonyms
SB 211475; BM 910228
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)