A-62198
A-62198 is a potent and selective renin inhibitor with antihypertensive activity. A-62198 reduces mean arterial pressure (MAP) in anesthetized, salt-deprived monkeys in a dose-dependent manner. A-62198 induced MAP reduction in normal monkeys that reached statistical significance at the highest dose and significantly inhibited plasma renin activity (PRA) at all doses.
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- CAS. Nr.: 117978-26-4
- Formel: C30H44N8O5
- Molecular Weight:596.72
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 117978-26-4
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Molecular Weight 596.72
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Formel C30H44N8O5
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SMILES
O[C@@H]([C@H](CN=[N+]=[N-])O)[C@@H](NC([C@H](CC1=CNC=N1)NC([C@H](CC2=CC=CC=C2)NC(C(C)C)=O)=O)=O)CC3CCCCC3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
A-62198 Related Classifications
HY-129737 Related Classifications
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