Benzoflavine
Benzoflavine is an acridine dye and photodynamic sensitizer that regulates embryonic development. Benzoflavine can adsorb to the surface of Arbacia sea urchin egg cell membranes, enhance the sensitivity of highly physiologically active embryonic regions to visible light radiation, and induce anterior-posterior developmental differences; at high concentrations, it can independently inhibit embryonic development without illumination, and its photosensitive response range covers the blue-violet region of visible light. Benzoflavine can be used in research fields such as developmental biology, organic synthesis, and photobiochemistry.
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- CAS. Nr.: 477-74-7
- Formel: C21H19N3
- Molecular Weight:313.40
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
In Vitro
Benzoflavine (in dilute seawater solution; gradient visible light irradiation) adsorbs to the cell membrane surface of fertilized Arbacia punctulata sea urchin eggs, inducing a photosensitizing effect of embryonic tissues to visible light radiation. Light treatment of this system induces four types of developmental phenotypes in Arbacia pluteus larvae, including irreversible differentiation inhibition, differentiation recovery after transient inhibition, complete overall tissue recovery, and tissue compensatory adaptation[1].
Benzoflavine (dilute seawater solution; continuous exposure to diffuse sunlight) induces differential adaptation and hyperplasia of the anterior median embryonic tissue in Arbacia larvae[1].
Benzoflavine (high-concentration seawater solution; incubated in the dark) inhibits the development of oral lobes and aboral arms in Arbacia embryos, resulting in a differential developmental inhibition effect[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS. Nr. 477-74-7
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Molecular Weight 313.40
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Formel C21H19N3
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SMILES
CC1=C(C=C2N=C3C=C(C(C)=CC3=C(C2=C1)C4=CC=CC=C4)N)N
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Benzoflavine Related Classifications
HY-121277 Related Classifications
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