CTT2274
CTT2274 is a prodrug of MMAE (HY-15162). CTT2274 is composed of a prostate-specific membrane antigen (PSMA)-binding scaffold, a biphenyl motif, a pH-sensitive phosphoramidate linker, and MMAE payload. CTT2274 shows selective binding to PSMA and delivers MMAE. CTT2274 inhibits prostate cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C119H159N17O33P2
- Molecular Weight:2417.58
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Chemical Information
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Molecular Weight 2417.58
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Formel C119H159N17O33P2
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SMILES
O[C@@H](C1=CC=CC=C1)[C@H](NC([C@@H]([C@H]([C@@H]2CCCN2C(C[C@H]([C@H]([C@@H](C)CC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(OC(N(CCN(P(OCC[C@H](NC(C4=CC=C(CN5C6=C(N=N5)C7=C(N(CC8=C6C=CC=C8)C(CCC(N[C@@H](CC9=CC=C(C%10=CC=CC=C%10)C=C9)C(NCCCCCC(N[C@@H](CCC(N[C@@H](CCCOP(N[C@@H](CCC(O)=O)C(O)=O)(O)=O)C(O)=O)=O)C(O)=O)=O)=O)=O)=O)C=CC=C7)C=C4)=O)C(O)=O)(O)=O)C)C)=O)C=C3)=O)C)=O)=O)C)OC)=O)OC)C)=O)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Bomba HN, et al. A Unique Prodrug Targeting the Prostate-Specific Membrane Antigen for the Delivery of Monomethyl Auristatin E. Bioconjug Chem. 2025 Feb 19;36(2):169-178.Bomba HN, et al. A Unique Prodrug Targeting the Prostate-Specific Membrane Antigen for the Delivery of Monomethyl Auristatin E. Bioconjug Chem. 2025 Feb 19;36(2):169-178. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CTT2274 Related Classifications
HY-168913 Related Classifications
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