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Art. -Nr.: HY-P992113

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Evabosmig

(Synonyms: AGA2118)

Evabosmig (AGA2118) is a bispecific antibody targeting SOST/sclerostin and DKK-1. Evabosmig binds to both SOST and DKK-1 simultaneously, activates the Wnt/β-catenin signaling pathway, and thereby potently promotes osteogenesis. Evabosmig can be used for the study of osteoporosis.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 3061142-96-6

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Evabosmig Chemical Structure

CAS. Nr.: 3061142-96-6

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Preis

Verfügbarkeit

Menge

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Isotype
- Species Reactivity
- Gene ID
- Accession
- Target
- Conjugated
- Reconsititution
- Format
- Anwendung
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Isotype

immunoglobulin (H-gamma4_L-kappa) (H-gamma4_L-kappa)

Species Reactivity

Human

Alle Wnt Isoform-spezifische Produkte anzeigen :

Gene ID

50964 [NCBI] & 22943 [NCBI]

Accession

Q9BQB4 & O94907

Target

SOST/Sclerostin & DKK1

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

IgG4-kappa

Anwendung

ELISA, FACS, Functional assay

Chemical Information

CAS. Nr. 3061142-96-6
SMILES

[Evabosmig]
Synonyms

AGA2118
Formulation

Please refer to the lot-specific COA for specific buffer information.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Inhibitory Antibodies User Guide (603 KB)

Verweise

[1]. Drake, M. T., et al. (2024, September). AGA2118, a bispecific monoclonal antibody neutralizing both sclerostin and DKK1, increased bone Formation, decreased bone resorption, and led to rapid BMD gains in a first in human, single-and multiple-dose, placebo-controlled, randomized study. In ASBMR 2024 Annual Meeting. ASBMR.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biologische Aktivität
- Beschreibung
- Isotype
- Species Reactivity
- Gene ID
- Accession
- Target
- Conjugated
- Reconsititution
- Format
- Anwendung
Chemical Information
Reinheit & Dokumentation
Verweise

Produktname:
Art. -Nr.:
Menge:
MCE Japan Authorized Agent:

Produktname:
CAS. Nr.:
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Reinheit:
Menge:

Evabosmig

PBS Buffer (1×)

DPBS Buffer (1×)

Cytotoxicity LDH Assay Kit

Alle Wnt Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Evabosmig Related Classifications

HY-P992113 Related Classifications