RCAN3 - RCAN family member 3 Gene

Also Known as RCN3; MCIP3; hRCN3; DSCR1L2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 11123

About RCAN3

Cytogenetic location: 1p36.11 Genomic coordinates (GRCh38): 1:24,502,344-24,541,040 (from NCBI)

This gene has 10 transcripts (splice variants), 203 orthologues and 2 paralogues. Broad expression in prostate (RPKM 18.2), lymph node (RPKM 9.0) and 22 other tissues.

Summary

Enables Phosphatase binding activity and troponin I binding activity. Predicted to be involved in calcium-mediated signaling. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RCAN3 Products (10)

mRNA Protein Name
NM_001251977.2 NP_001238906.1 calcipressin-3 isoform 1
NM_001251978.1 NP_001238907.1 calcipressin-3 isoform 1
NM_001251979.2 NP_001238908.1 calcipressin-3 isoform 1
NM_001251980.1 NP_001238909.1 calcipressin-3 isoform 2
NM_001251981.2 NP_001238910.1 calcipressin-3 isoform 3
NM_001251982.1 NP_001238911.1 calcipressin-3 isoform 4
NM_001251983.2 NP_001238912.1 calcipressin-3 isoform 5
NM_001251984.2 NP_001238913.1 calcipressin-3 isoform 5
NM_001251985.1 NP_001238914.1 calcipressin-3 isoform 6
NM_013441.4 NP_038469.1 calcipressin-3 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables phosphatase binding IPI
IPI: Inferred from physical interaction
26248042 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16516408 GOA
enables troponin I binding IPI
IPI: Inferred from physical interaction
16516408 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RCAN3 Protein Structure

Calcipressin

Calcipressin: Calcipressin (57 - 225)

  • 0
  • 100
  • 200
  • 241 a.a.
Protein Preferred Names Protein Names

calcipressin-3

  • Down syndrome candidate region 1-like 2

RCAN3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Cross
RCAN3 Q9UKA8 P0C6X7-PRO_0000037309 Human SARS coronavirus P0C6X7-PRO_0000037309
Y2H Pooling
22046132
Cross
RCAN3 Q9UKA8 P0C6X7-PRO_0000037309 Human SARS coronavirus P0C6X7-PRO_0000037309
Lumier
22046132
Intra
RCAN3 Q9UKA8 TRIM23 Homo sapiens P36406
Y2H Array
32296183
Intra
RCAN3 Q9UKA8 GRB10 Homo sapiens Q13322
Y2H Array
25814554
Intra
RCAN3 Q9UKA8 GRB10 Homo sapiens Q13322
Lumier
25814554
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Down Syndrome

  • Trisomy 21

  • Complete Trisomy 21 Syndrome

  • Down'S Syndrome

  • Trisomy 21 Syndrome

  • Down'S Syndrome - Trisomy 21

  • Downs Syndrome

  • G Trisomy

  • 47,Xx,+21

  • 47,Xy,+21

  • Trisomy G

  • Down Syndrome, Susceptibility To

  • Chromosome 21 Trisomy

  • Trisomy 21 Nos

  • Abnormal Autosomes 21
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS11781 RCAN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris RCAN3 VGNC VGNC:45438
Mus musculus RCAN3 MGD MGI:1858220
Macaca mulatta RCAN3 VGNC VGNC:76875
Rattus norvegicus RCAN3 RGD RGD:1311826
Bos taurus RCAN3 VGNC VGNC:33822
Others RCAN3 NCBI