HDAC8-IN-11
HDAC8-IN-11 is a ligand for target protein for pROTAC.
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- CAS. Nr.: 3035977-24-0
- Formel: C16H25N3O2
- Molecular Weight:291.39
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>33.3 μM
Compound: 6
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
|
[PMID: 39089850] |
| A549 | IC50 |
>33.3 μM
Compound: 6
|
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
Antiproliferative activity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
|
[PMID: 39089850] |
| HCT-116 | IC50 |
>33.3 μM
Compound: 6
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
|
[PMID: 39089850] |
| HCT-116 | IC50 |
>33.3 μM
Compound: 6
|
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
|
[PMID: 39089850] |
| Jurkat | IC50 |
>33.3 μM
Compound: 6
|
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
|
[PMID: 39089850] |
| Jurkat | IC50 |
>33.3 μM
Compound: 6
|
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
Antiproliferative activity against human Jurkat cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
|
[PMID: 39089850] |
| THP-1 | IC50 |
>33.3 μM
Compound: 6
|
Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth measured after 72 hrs by MTS assay
|
[PMID: 39089850] |
| THP-1 | IC50 |
>33.3 μM
Compound: 6
|
Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
Antiproliferative activity against human THP-1 cells assessed as inhibition of cell growth measured after 72 hrs in presence of tert-butyl 2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)acetate by MTS assay
|
[PMID: 39089850] |
Chemical Information
-
CAS. Nr. 3035977-24-0
-
Molecular Weight 291.39
-
Formel C16H25N3O2
-
SMILES
O=C(C)NCC1=CC=C(C(NNCCCCCC)=O)C=C1
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Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)