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Art. -Nr.: HY-182578

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Mimosinamine

Mimosinamine is a hydroxylase inhibitor with Fe²⁺ chelating activity. Mimosinamine inhibits bovine adrenal tyrosine hydroxylase, rat liver phenylalanine hydroxylase, and rat brainstem tryptophan hydroxylase. Mimosinamine can be used in the research of hypertension.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 37053-15-9
Formel: C₇H₁₀N₂O₂
Molecular Weight:154.17

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Mimosinamine Chemical Structure

CAS. Nr.: 37053-15-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Protokoll (1)
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Mimosinamine (Compound 6e) (0-1 mM; 20-60 min) inhibits partially purified rat liver phenylalanine hydroxylase, partially purified bovine adrenal tyrosine hydroxylase, and crude rat brainstem tryptophan hydroxylase in vitro, with maximum inhibition rates of 58.3%, 66.1% and 35.0% at a concentration of 1.0 mM^[1].
Mimosinamine chelates 16% of Fe²⁺ in cell-free polarographic assays at pH 7.0^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

CAS. Nr. 37053-15-9
Molecular Weight 154.17
Formel C₇H₁₀N₂O₂
SMILES

O=C1C=CN(CCN)C=C1O
Structure Classification
- Alkaloids
- Piperidine Alkaloids
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Protokoll

All Signal Pathway Related

Research Protocol for Cardiovascular Diseases
Cardiovascular disease can be modeled as maladaptive cardiac remodeling, where ischemic injury or pressure overload activates inflammatory signaling, fibroblast activation, extracellular-matrix deposition, cardiomyocyte hypertrophy, vascular remodeling, and progressive ventricular dysfunction. The TGF-β/SMAD axis is a central profibrotic pathway after myocardial injury and pressure overload, while innate immune and cytokine pathways regulate leukocyte recruitment, scar formation, and adverse remodeling. Key unresolved questions include which inflammatory signals are reparative versus harmful, when fibrosis is protective versus maladaptive, and whether pathway inhibition improves function without weakening necessary infarct healing or compensatory remodeling.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Hare LE, Lu MC, Sullivan CB, Sullivan PT, Counsell RE, Weinhold PA. Aromatic amino acid hydroxylase inhibitors. 3. In vitro inhibition by azadopamine analogs. J Med Chem. 1974 Jan;17(1):1-5. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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