FGF-3
FGF-3 shows one of the narrowest expression patterns of the canonical FGF ligands. During development it is confined largely to the otic vesicle, where it supports inner-ear formation, and to the developing tooth and hindbrain; in adults it remains detectable mainly in the brain. FGF-3 signals preferentially through the FGFR1b and FGFR2b isoforms. The human FGF3 locus at chromosome 11q13 is co-amplified with CCND1 in a subset of breast, head-and-neck and bladder cancers, where FGF3 overexpression is thought to contribute to tumor growth. Recombinant FGF-3 protein supports inner-ear and dental research, otic differentiation protocols and receptor-binding studies.
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FGF-3 Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
