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Art. -Nr.: HY-190191

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QC-65

QC-65 is a HO-1/HO-2 inhibitor with IC₅₀ = 4.0 μM for HO-1 and IC₅₀ = 11.3 μM for HO-2. QC-65 can be used in research on HO-1-mediated related diseases, such as cancer.

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CAS. Nr.: 741628-94-4
Formel: C₁₃H₁₄N₂O
Molecular Weight:214.26

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

QC-65 Chemical Structure

CAS. Nr.: 741628-94-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

QC-65 is a HO-1/HO-2 inhibitor with IC₅₀ = 4.0 μM for HO-1 and IC₅₀ = 11.3 μM for HO-2. QC-65 can be used in research on HO-1-mediated related diseases, such as cancer^[1].

IC₅₀ & Target

^[1]

HO-1

4.0 μM (IC₅₀)

HO-2

11.3 μM (IC₅₀)

Alle Heme Oxygenase (HO) Isoform-spezifische Produkte anzeigen :

HO-1
HO-2

In Vitro

QC-65 (1-100 μM; 60 min at 37 °C) inhibits rat spleen HO-1 and rat brain HO-2 with IC₅₀ values of 4.0 μM and 11.3 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 741628-94-4
Molecular Weight 214.26
Formel C₁₃H₁₄N₂O
SMILES

O=C(CCC1=CC=CC=C1)CN2C=CN=C2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Fallica AN, et al. Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent Antiproliferative Activity. Journal of medicinal chemistry. 2021 Sep 23;64(18):13373-13393. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
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QC-65

Alle Heme Oxygenase (HO) Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Beschreibung

IC50 & Target

In Vitro

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

QC-65 Related Classifications

HY-190191 Related Classifications

Bioz

Keywords

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