SARS 3CLpro-IN-1
SARS 3CLpro-IN-1 (Compound 3b) is a SARS 3CL protease inhibitor with an IC50 value of 95 μM, as a specific stereo isomer of the octahydroisochromene scaffold, directs the P1 site imidazole.
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- CAS. Nr.: 2409178-86-3
- Formel: C22H38N4O2
- Molecular Weight:390.56
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
IC50: 95 μM (SARS 3CL protease) [1]
In Vitro
SARS 3CLpro-IN-1 (Compound 3b) has high active (IC50=95 μM) and had a (1S, 3S)-configuration in the ring system[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS. Nr. 2409178-86-3
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Molecular Weight 390.56
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Formel C22H38N4O2
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SMILES
O=C[C@@H](NC[C@H]1O[C@H](CN(CCCC)C)[C@@]2([H])CCCC[C@]2([H])C1)CC3=CNC=N3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SARS 3CLpro-IN-1 Related Classifications
HY-150691 Related Classifications
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