AX-9657
KRP-109 is a neutrophil elastase (NE) inhibitor with activity in reducing lung inflammation. KRP-109 improves survival in mouse models and reduces the number of neutrophils and inflammation in the alveolar walls. KRP-109 significantly reduced cell and neutrophil counts in bronchoalveolar lavage fluid, as well as cytokine levels such as interleukin 1β and macrophage inflammatory protein 2. KRP-109 can be used in the research of severe pneumonia.
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- CAS No.: 1015439-77-6
- Formule: C22H26N4O3
- Masse moléculaire:394.47
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Activité biologique
Chemical Information
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CAS No. 1015439-77-6
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Masse moléculaire 394.47
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Formule C22H26N4O3
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SMILES
O=C1OC(C2=CC=CN=C2N3C[C@@H](N(C)C)CC3)=NC4=CC(OC)=CC(CC)=C14
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AX-9657 Related Classifications
HY-11046 Related Classifications
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