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Cat. No.: HY-163825A

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(E)-RNB-61

(E)-RNB-61 is the E configuration of RNB-61 (HY-163825). RNB-61 is an orally active cannabinoid CB2 receptor (CB2R) agonist with a K_i range of 0.13 nM to 1.81 nM. RNB-61 has renal protective and/or anti-fibrotic effects.

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CAS No.: 1217403-51-4
Formule: C₂₅H₃₄F₃N₃O₃
Masse moléculaire:481.55

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

(E)-RNB-61 Chemical Structure

CAS No.: 1217403-51-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

IC₅₀ & Target^[1]

CB2

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Chemical Information

CAS No. 1217403-51-4
Masse moléculaire 481.55
Formule C₂₅H₃₄F₃N₃O₃
SMILES

O=C(C1=C(C=CC(C(F)(F)F)=C1)OCC(C)(O)C)/N=C2N(N(C(C(C)(C)C)=C/2)C)CC3CCC3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Andrea Chicca, et al. A Highly Potent, Orally Bioavailable Pyrazole-Derived Cannabinoid CB2 Receptor- Selective Full Agonist for In Vivo Studies. bioRxiv [Preprint]. 2024 Apr 29:2024.04.26.591311. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

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Molecular Weight Molecular Weight

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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(E)-RNB-61

Voir tous les produits spécifiques à Isoform Cannabinoid Receptor