Ebrotidine (Standard)
Ebrotidine (Standard) (FI3542 (Standard)) is the analytical standard of Ebrotidine (HY-15538). This product is intended for research and analytical applications. Ebrotidine (FI3542) is a competitive histamine H2 receptor (histamine H2 receptor) antagonist with gastric acid secretion inhibitory and gastric mucosal protective effects. Ebrotidine alleviates gastric mucosal injury and epithelial cell apoptosis induced by Indomethacin (HY-14397) and Helicobacter pylori LPS (HY-D1056), and accelerates chronic gastric ulcer healing by promoting rapid recovery of IL-4 and inhibiting TNF-α, endothelin-1 (ET-1) and NOS-2. Ebrotidine can be used in studies on gastric ulcer healing, NSAID-induced gastric mucosal injury, Helicobacter pylori-associated gastritis, and H2 receptor-mediated gastric mucosal protection mechanisms.
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- Pureté : 98%
- CAS No.: 100981-43-9
- Formule: C14H17BrN6O2S3
- Masse moléculaire:477.42
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 100981-43-9
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Masse moléculaire 477.42
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Formule C14H17BrN6O2S3
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SMILES
O=S(C1=CC=C(Br)C=C1)(/N=C/NCCSCC2=CSC(NC(N)=N)=N2)=O
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Synonyms
FI3542 (Standard)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Ebrotidine (Standard)
- 100981-43-9
- FI3542 (Standard)
- Reference Standards
- Histamine Receptor
- Interleukin Related
- TNF Receptor
- Endothelin Receptor
- indomethacin-induced gastric mucosal injury
- gastric mucosal hyperplasia
- Helicobacter pylori
- acute gastritis
- Swiss CD-1 SPF mice
- gastric acid secretion
- ECL cell
- histamine H2-receptor
- chronic gastric ulcer
- antral G-cell
- Inhibitor
- inhibitor
- inhibit