Tle4 - TLE family member 4, transcriptional corepressor Gene

Also Known as Esp2; Grg-4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25565

Summary

Predicted to enable DNA-binding transcription factor binding activity; chromatin binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway; cellular response to leukemia inhibitory factor; and negative regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human TLE4 (TLE family member 4, transcriptional corepressor). [provided by Alliance of Genome Resources, Apr 2022]

Tle4 Products (2)

mRNA Protein Name
NM_001414041.1 NP_001400970.1 transducin-like enhancer protein 4 isoform 1
NM_019141.3 NP_062014.2 transducin-like enhancer protein 4 isoform 2
Protein Preferred Names Protein Names

transducin-like enhancer protein 4

  • groucho-related protein 4

  • transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)

  • transducin-like enhancer of split 4, E(spl) homolog

  • transducin-like enhancer of split 4, homolog of Drosophila E(spl)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS14566 TLE4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21444 Tle4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27962 Tle4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tle4 NCBI NCBI:7091