TRAPPC1 - trafficking protein particle complex subunit 1 Gene

Also Known as BET5; MUM2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 58485

About TRAPPC1

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,930,345-7,931,999 (from NCBI)

This gene has 7 transcripts (splice variants), 183 orthologues and 1 paralogue. Ubiquitous expression in placenta (RPKM 52.2), lymph node (RPKM 50.3) and 25 other tissues.

Summary

This gene product plays a role in vesicular transport of proteins to the Golgi apparatus from the endoplasmic reticulum. The encoded protein is a component of the multisubunit transport protein particle (TRAPP) complex. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

TRAPPC1 Products (2)

mRNA Protein Name
NM_001166621.1 NP_001160093.1 trafficking protein particle complex subunit 1
NM_021210.5 NP_067033.1 trafficking protein particle complex subunit 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRAPPC1 Protein Structure

Sybindin

Sybindin: Sybindin-like family (3 - 136)

  • 0
  • 100
  • 145 a.a.
Protein Preferred Names Protein Names

trafficking protein particle complex subunit 1

  • BET5 homolog

TRAPPC1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
TRAPPC1 Q9Y5R8 TRAPPC3 Homo sapiens O43617
Y2H Array
32296183
Intra
TRAPPC1 Q9Y5R8 TRAPPC3 Homo sapiens O43617
Anti Tag CoIP
28514442
Intra
TRAPPC1 Q9Y5R8 TRAPPC3 Homo sapiens O43617
Anti Tag CoIP
33961781
Intra
TRAPPC1 Q9Y5R8 TRAPPC3 Homo sapiens O43617
Anti Tag CoIP
35271311
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Spondyloepiphyseal Dysplasia Tarda, X-Linked

  • Spondyloepiphyseal Dysplasia Tarda

  • X-Linked Spondyloepiphyseal Dysplasia Tarda

  • SEDT

  • Sed Tarda, X-Linked

  • Spondyloepiphyseal Dysplasia, Late

  • Spondyloepiphyseal Dysplasia Tarda X-Linked

  • Sed

  • X Linked Spondyloepiphyseal Dysplasia Tarda

  • X-Linked Spondyloepiphyseal Dysplasia

  • Late Onset Spondyloepiphyseal Dysplasia

  • Sed Tarda

  • X-Linked Sed

  • X-Linked Sedt

  • Dysplasia, Spondyloepiphyseal, Tarda

  • Spondyloepiphyseal Dysplasia
Melanoma

  • Malignant Melanoma

  • Cutaneous Melanoma

  • Naevocarcinoma

  • Malignant Melanomas
Autosomal Recessive Intellectual Developmental Disorder

  • Mental Retardation, Autosomal Recessive

  • Autosomal Recessive Mental Retardation

  • Autosomal Recessive Non-Syndromic Mental Retardation

  • Autosomal Recessive Non-Syndromic Intellectual Disability
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS14985 TRAPPC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TRAPPC1 VGNC VGNC:36284
Mus musculus TRAPPC1 MGD MGI:1098727
Canis familiaris TRAPPC1 VGNC VGNC:47777
Macaca mulatta TRAPPC1 VGNC VGNC:79208
Felis catus TRAPPC1 VGNC VGNC:66508
Rattus norvegicus TRAPPC1 RGD RGD:1311365
Others TRAPPC1 NCBI