CHCHD5 - coiled-coil-helix-coiled-coil-helix domain containing 5 Gene

Also Known as CHTM1; MIC14; MIX14; C2orf9

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84269

About CHCHD5

Cytogenetic location: 2q14.1 Genomic coordinates (GRCh38): 2:112,584,447-112,589,040 (from NCBI)

This gene has 5 transcripts (splice variants), 189 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 3.7), kidney (RPKM 2.9) and 25 other tissues.

Summary

Predicted to be located in mitochondrial intermembrane space. [provided by Alliance of Genome Resources, Apr 2022]

CHCHD5 Products (5)

mRNA Protein Name
NM_001304353.2 NP_001291282.1 coiled-coil-helix-coiled-coil-helix domain-containing protein 5 isoform b
NM_001304354.2 NP_001291283.1 coiled-coil-helix-coiled-coil-helix domain-containing protein 5 isoform b
NM_001371322.1 NP_001358251.1 coiled-coil-helix-coiled-coil-helix domain-containing protein 5 isoform b
NM_001371323.1 NP_001358252.1 coiled-coil-helix-coiled-coil-helix domain-containing protein 5 isoform b
NM_032309.4 NP_115685.1 coiled-coil-helix-coiled-coil-helix domain-containing protein 5 isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CHCHD5 Protein Structure

CHCH

CHCH: CHCH domain (58 - 91)

  • 0
  • 100
  • 110 a.a.
Protein Preferred Names Protein Names

coiled-coil-helix-coiled-coil-helix domain-containing protein 5

  • mitochondrial intermembrane space cysteine motif protein of 14 kDa homolog

CHCHD5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
CHCHD5 Q9BSY4 HCCS Homo sapiens P53701
Anti Tag CoIP
33961781
Intra
CHCHD5 Q9BSY4 INCA1 Homo sapiens Q0VD86
Y2H Array
32296183
Intra
CHCHD5 Q9BSY4 INCA1 Homo sapiens Q0VD86
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS02602 CHCHD5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CHCHD5 VGNC VGNC:60840
Mus musculus CHCHD5 MGD MGI:1913420
Bos taurus CHCHD5 VGNC VGNC:57347
Rattus norvegicus CHCHD5 RGD RGD:1307809
Macaca mulatta CHCHD5 VGNC VGNC:82122
Canis familiaris CHCHD5 VGNC VGNC:39197
Others CHCHD5 NCBI