GNE-431
GNE-431 is a potent, selective and noncovalent “pan-BTK” inhibitor against C481R, T474I and T474Ms mutants. GNE-431 shows potency against wild-type BTK (IC50= 3.2 nM) and potency against C481S mutant (IC50= 2.5 nM). GNE-431 is proming for rasearch of haematological disorders and autoimmune diseases.
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- CAS No.: 1433820-83-7
- Formule: C30H32N10O2
- Masse moléculaire:564.64
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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CAS No. 1433820-83-7
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Masse moléculaire 564.64
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Formule C30H32N10O2
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SMILES
O=C1N(C2=NC=CC(C3=NN4C(C(NC5=NN6C(CN(C)CC6)=C5)=C3)=NC=C4)=C2CO)CCN7C1=CC8=C7CCCC8
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)