JMX0254
JMX0254 is an orally active and potent inhibitor of the dengue virus NS4B protein. JMX0254’s EC50 for DENV-1, DENV-2, and DENV-3 are 0.78 µM, 0.16 µM, and 0.035 µM, respectively. JMX0254 can be used for research on viral infections.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 2375960-04-4
- Formule: C25H25Cl2N5O2
- Masse moléculaire:498.40
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
>10 μM
Compound: 15; JMX0254
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Cytotoxicity in human HuH7 replicon cells infected with Dengue virus 2 NGC assessed as reduction in cell viability incubated for 48 hrs by Cell-titer-Glo reagent based assay
Cytotoxicity in human HuH7 replicon cells infected with Dengue virus 2 NGC assessed as reduction in cell viability incubated for 48 hrs by Cell-titer-Glo reagent based assay
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[PMID: 31403780] |
Chemical Information
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CAS No. 2375960-04-4
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Masse moléculaire 498.40
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Formule C25H25Cl2N5O2
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SMILES
O=C1[C@@]2(C3=C(NC(C2)=O)N(N=N3)[C@H](C4=CC=C(C=C4)Cl)C)C5=CC(Cl)=CC=C5N1CCC(C)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JMX0254 Related Classifications
HY-149467 Related Classifications
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