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Cat. No.: HY-124158

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KR-60436

KR-60436 is a reversible H⁺/K⁺-ATPase inhibitor. KR-60436 can potently inhibit the metabolism of CYP1A2 substrates.

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CAS No.: 220853-65-6
Formule: C₂₂H₂₂F₃N₃O₃
Masse moléculaire:433.42

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

KR-60436 Chemical Structure

CAS No.: 220853-65-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

KR-60436 is a reversible H⁺/K⁺-ATPase inhibitor. KR-60436 can potently inhibit the metabolism of CYP1A2 substrates^[1].

Chemical Information

CAS No. 220853-65-6
Masse moléculaire 433.42
Formule C₂₂H₂₂F₃N₃O₃
SMILES

FC(F)(F)OC1=C2N=C(C3=C(C2=CC=C1)N(CC3)C4=CC=C(C=C4C)OC)NCCO
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ji HY, et al. Characterization of human liver cytochrome P450 enzymes involved in the metabolism of a new H+/K+-ATPase inhibitor KR-60436. Toxicol Lett. 2005 Jan 15;155(1):103-14. [Content Brief]

Calculators

Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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